Meeting Program 2017

48th Annual Meeting

September 8 - 10, 2017 
Atlanta Marriott Buckhead Hotel and Conference Center

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Friday, September 8, 2017
Time Event Location
3:00 - 6:00pm CHECK-IN and REGISTRATION
6:00pm   Welcome Reception
7:00pm Welcome  PRS President Anthony Gregg MD
7:10pm Dinner
8:00 - 8:45pm Mead Johnson Nutrition Speaker –Erik Herzog PhD: Circadan Regulation of Birth. The mechanisms underlying pre-term birth are largely unknown.  This talk will pursue the hypothesis that genetic or environmental disruption of daily rhythms intrinsic to the mom or feus puts a pregnancy at risk for premature delivery.  Combining real-time imaging of birth and gene expression in reprooductive and fetal tissues in mice- this work has identified human polymorphisms that alter pregnancy outcomes. 
Moderator: Ernie Graham MD 
Erick Herzog PhD
Saturday, September 9, 2017
Time Event Location
6:45  - 7:45am BREAKFAST
8:00- 8:45am March of Dimes Speaker –Phyllis Dennery MD:The Bioenergetics of Neonatal Lung Injury and Repair - Mitochondria are central to oxidative metabolism and - therefore - play an important role in regulating reactive oxygen species and nutrient utilization that impact injury and repair.  This talk will discuss the implications of metabolism in neonatal lung disease.
Moderator: Jeff Reese MD 
Phyllis Dennery MD
9:00 - 9:20am Abbott Nutrition Early Career Speaker– Tomo Tarui MD: Developing New diagnostic technologies for fetal neurological disorders
Moderator: Lisa Joss-Moore PhD
9:20 - 9:40am Abbott Nutrition Early Career Speaker –Charitharth Vivek Lal MD: The Role of Microbiota Induced Matrikines in Bronchopulmonary Dysplasia –Moderator:  Lisa Joss-Moore PhD
10:00 - 10:30am BREAK
10:30- 11:15am NIH/NICHD Speaker: Diana Bianchi MD –A Vision for the Future of NICHD - Dr. Bianchi (A past President of the PRS) will give an overview of her vision for the future of NICHD with a particular emphasis on results of a two-year analysis of individual and institutional training awards.   She will also discuss shared data resources such as the DASH and Placental Atlas networks and opportunities for collaboration with other NIH institutes. –Moderator: Ian Bird PhD
11:15 -11:30am QUESTIONS AND ANSWERS - Diana Bianchi MD
11:30- 12:30pm Business Meeting
Anthony Gregg MD and Paul Rozance MD
3:30- 4:50pm Liley Lectureship and Award Winners –Charles Wood PhD and Maureen Keller-Wood PhD – Using Systems Biology to Understand Maternal-Fetal Physiology. Physiological processes are inherently complex networks of overlapping and complementary control systems.  Candidate regulations are often investigated as isolated biochemical or molecular pathways.  In this talk we will explore the concept of a nonlinear approach to discovery and validation of important regulatory processes in pregnancy and fetal development. –Moderator: Tony Gregg MD 
4:50 - 5:05pm QUESTIONS AND ANSWERS - Charles Wood PhD and Maureen Keller-Wood PhD 
5:05 - 5:30pm BREAK
5:30 - 5:50pm PSANZ-PRS Mont Liggins Early Career Speaker –Teresa MacDonald: The Fetal Longitudinal Assessment of Growth (FLAG) Study - Reduced third trimester growth velocity in fetuses of a normal birthweight is associated with placental insufficiency. –Moderator: Frank Bloomfield MBChB PhD
5:50 - 6:10pm   Mead Johnson Nutrition Early Career Speaker – Leticia Camacho PhD: Oxygen and Glucose Correction Improves Insulin Secretion in Sheep Fetuses with Placental Insufficiency –Lisa Joss-Moore PhD
6:10 -6:30pm Mead Johnson Nutrition Early Career Speaker –Jennifer Thompson PhD: Maternal Metabolic State and Cardiometabolic Risk in the Offspring –Moderator: Lisa Joss-Moore PhD
6:30 -6:50pm PSANZ-PRS and Mead Johnson Nutrition Early Career Speakers. QUESTIONS AND ANSWERS
7:30 pm Dinner - Reception
8:30pm Awards
Sunday, September 10, 2017
Time Event Location
6:45 - 8:00am BREAKFAST
8:00 - 8:45am NIH/NICHD Speaker –Dinesh Shah MD: Pathway to Preeclampsia.  Renin Angiotensin System plays a major role in the maintenance of pressure and volume in the body.  RAS probably plays a significant role in the pathogenesis of preeclampsia.  We will discuss circulating vs tissue based RAS.  Understanding the blood-flow and perfusion in the uterus and placenta and activation of the local RAS is critical in understanding pathway to preeclampsia. –Moderator: Louise Laurent MD PhD
8:45-9:00am QUESTIONS AND ANSWERS Dinesh Shah MD
9:00 - 9:45am Abbott Nutrition Speaker –Frank Bloomfield MBChB PhD: Fetal and Neonatal Nutrition and the Developing Pancreas .The pancreas undergoes significant development and maturation in late gestation and during the early postnatal period.  Nutrition even within the range of normal practice - of the mother - fetus and newborn - can have significant effects on this development. –Moderator: Sean Limesand PhD
9:45 10:00am QUESTIONS AND ANSWERS Frank Bloomfield MBChB PhD
10:00 -10:30am BREAK
10:30- 11:15am Invited Member Lecturer –Clyde Wright MD: Oxygen Toxicity in the Premature Lung: Can We Separate the Signal from the Inevitable Consequence?  Recognize that exposing the developing lung to oxygen toxicity is a "necessary evil" in the NICU.  Recognize that the developing lung is uniquely resistant to the effects of oxygen toxicity.  Identify the unique role played by hyperoxia-induced NFkB activity in the developing lung.  Explain why understanding "NFkB transcriptional selectivity" is necessary to attenuate hyperoxic lung injury. –Moderator: Trent Tipple MD 
11:15am-11:30am QUESTIONS AND ANSWERS Clyde Wright MD
11:30 - 12:15 pm Invited Member Speaker –Emin Maltepe MD PhD: Using Sheep Models to Study Pulmonary Hypertension and Oxygen Delivery Biotherapeutics. Sheep models of neonatal and pediatric cardiovascular disease have been central to advancing the care of these patients.  Here we investigate a physiologically relevant model of pulmonary hypertension triggered by pulmonary overcirculation in newborn lams as well as the utility of a novel class of non-hemoglobin based oxygen carriers in hypoxic as well as anemic hypoxia lamb models. –Moderator: Sonnet Jonker PhD
12:15 - 12:30 pm QUESTIONS AND ANSWERS Emin Maltepe MD PhD


Memories from 2017 - Atlanta Marriott Buckhead Hotel